Free Biochemistry MCQs Mock Test Online with Answers

Q1 : Ferritin – an inactive form of iron is stored in_____________?

A: Gut B: Spleen C: Liver D: All of the above

Q2 : Muscle glycogen, which cannot contribute to blood glucose due to the absence of which enzymes ?

A: Phosphoglutamase B: Branching enzyme C: Debranching enzyme D: Glucose-6-phosphotase

Q3 : In TCA, substrate level phospherylation takes place in______________?

A: Alpha ketoglutrate to succinyl CoA B: Succinyl CoA to Succinate C: Succinate to fumarate D: Oxalocetate to citrate

Q4 : Glycogen breakdown leads to formation of______________?

A: Glucose B: Lactic acid C: Glucose & Lactic acid D: Glycoprotein

Q5 : Oligosaccharide is________________?

A: Glucose B: Gructose C: Maltose D: Dextrin

Q6 : A patient of type 2 diabetes mellitus is given nutrition rich in________________?

A: Proteins B: Carbohydrates C: . Fat D:

Q7 : Which of the organelles contain DNA_________________?

A: Nucleus B: Golgi apparatus C: Nucleolus D: Golgi apparatus

Q8 : All are true regarding glucose 6 phosphate deficiency except______________?

A: Hyperuricemia B: Hyperglycemia C: Defective cori cycle D: Increased mobilization of glycogen from liver

Q9 : Rate limiting step in adrenaline synthesis is conversion of____________?

A: Tyrosine to dopa B: Phenylalanine to tyrosine C: Dopa to dopamine D: Dopamine to nor epinephrine

Q10 : The main site of fluoride inhibition in the Embden Meyerhof pathway of acid____________?

A: ATPase B: Enolase C: Pyruvate Kinase D: Fructose 6 phosphatase

Q11 : The sigma subunit of prokaryotic RNA polymerase_______________?

A: Binds the antibiotic Rifampicin B: Is inhibited by a-amanitin C: Specifically recognizes the promoter site D: Is part of the core enzyme

Q12 : FSH, LH, TSH acts through_________________?

A: Cyclic AMP B: Cyclic GMP C: Adenosine cyclate D: Calcium release

Q13 : Coenzyme, in an enzymatic reaction usually functions to_____________?

A: Activate the substrate B: Increase the active sites of apoenzyme C: Enhance the specificity of apoenzyme D: Accept one of the cleavage products

Q14 : Enzymes help by____________?

A: Lowering the activation energy B: Increasing the substrate concentration C: Decreasing the surface tension D: Increasing the activation energy

Q15 : Glucose can be synthesized from all except_____________?

A: Amino acids B: Glycerol C: Acetoacetate D: Lactic acid

Q16 : Which of the following has a ketogenic effect on livers______________?

A: Insulin B: Glucagon C: GH D: Androgen

Q17 : Translation occurs at______________?

A: Mitochondria B: Centrosome C: Nucleus D: Ribosome

Q18 : In the physiological system, nitric oxide is known to act through_______________?

A: Cyclic AMP B: Calcium ions C: Cyclic GMP D: Prostacyclins

Q19 : Which of the following is not a ketone body______________?

A: Acetone B: Acetic acid C: Acetocetate D: Beta hydroxybutyric acid

Q20 : Which of the following statement is TRUE? The hydrolysis of lactose yields glucose and galactose_____________?

A: The hydrolysis of lactose yields glucose and galactose B: The hydrolysis of maltose yields glucose and fructose C: The hydrolysis of sucrose yields only glucose D: All of the above statements are true

Q21 : HMG CoA reductase is inhibited by_____________?

A: Clofibrate B: Gemfibrosil C: Lovastatin D: cholestyramine

Q22 : Limiting factory for fatty acid synthesis_________________?

A: Aceto acetate synthetase B: Acyl transferase C: Acetyl CoA carboxylase D: Biotin

Q23 : The protein rich in basic amino acids, which functions in the packaging of DNA is chromosomes is______________?

A: Histone B: Collagen C: Hyaluronic acid binding protein D: Fibrinogen

Q24 : The following is not a carrier protein________________?

A: Cerruloplasmin B: Transferrin C: Transcobalamine D: Haptoglobulin

Q25 : Rate limiting step in cholesterol synthesis is_______________?

A: HMG CoA synthetase B: HMG CoA lyase C: HMG CoA reductase D: Mevalonate synthetase

Q26 : Ketone body formation takes place in_______________?

A: Liver B: Kidney C: Spleen D: Blood

Q27 : The transmembrane adhesive molecules present in hemi desmosomes which specifically binds to basal lamina glycoprotein laminin are______________?

A: Integrin a6-B4 B: The catenins desmoplakin C: cadherins desmoglein D: a and B catenin

Q28 : Bile acids are formed from__________?

A: Cholesterol B: Aminoacids C: Bilirubin D: Lipoproteins

Q29 : Generation of free radicals occurs by all of the following mechanism EXCEPT_____________?

A: Normal metabolism B: Oxygen toxicity C: Reperfusion after ischemic injury D: All of the above

Q30 : Which of the following organs cannot use ketone bodies_______________?

A: Brain B: Liver C: Kidney D: Spleen

Q31 : Cholesterol levels in abnormal person should be preferably less than_____________?

A: 200 mg/dl B: 180 mg/dl C: 150 mg/dl D: 120 mg/dl

Q32 : All are genetic amino acid deficiency disease except___________?

A: Phenyl ketonuria B: Alkaptonuria C: Homocystinuria D: 6alactosemia

Q33 : In TCA cycle or tricarboxylic acid cycle, which is first formed________________?

A: Isocitrate B: Citrate C: Succinate D: Fumarate

Q34 : Saponification means hydrolysis of fats by________________?

A: Acid B: Alkali C: Water D: Enzymes

Q35 : An enzyme not involved in glycolysis is______________?

A: Enolase B: Phosphoglycero mutase C: Aldolase D: Glycerophosphate dehydrogenase

Q36 : Inactive precursors of enzymes are known as_______________?

A: Apoenzymes B: Coenzymes C: Proenzymes D: Holoenzymes

Q37 : The following is false about tryptophan_____________?

A: Non-essential amino acid B: Involved in serotonin synthesis C: Involved in niacin synthesis D: Involved in melatonin in synthesis

Q38 : Competitive enzyme inhibition will cause_____________?

A: Decrease of km and increase of Vmax B: increase of km and increase of Vmax C: Decrease of km and decrease of Vmax D: Increase of km and Unchanged of Vmax

Q39 : Dehydrogenase used as coenzymes all of the following, except________________?

A: FMN B: FAD C: NADP+ D: Ferro protoporphyrin

Q40 : The enzyme that splits hydrogen peroxide into water and oxygen is_____________?

A: Cytochromes B: Cytochrome P 450 C: Super oxide dismutase D: Catalase

Q41 : The process by which a base sequence of messenger RNA is synthesized (by a RNA polymerase) on a template of complementary DNA is called______________?

A: Transcription B: Transduction C: Translation D: . Translocation

Q42 : Number of ATP molecules generated in the conversion of glycogen of lactate is_____________?

A: 2 B: 36 C: 38 D: 32

Q43 : Unsaturated fatty acids are converted to______________?

A: Prostaglandins B: Cholesterol C: Cell membrane lipid D: Saturated fatty acid

Q44 : Ketone bodies are normally synthesized from______________?

A: Acetyl-CoA B: Glucose C: Glycerol D: Acetone

Q45 : ALbumin is synthesized by_____________?

A: Liver B: Kidney C: Muscle D: Spleen

Q46 : Which is the by product of the urea cycle_______________?

A: Aspartate B: Succinate C: Ornithine D: Fumarate

Q47 : Increase in pyruvate and lactate is seen in which of the following deficiency ?

A: Thiamine B: Pyridoxine C: Niacin D: Vitamin C

Q48 : An essential for the conversion of glucose to glycogen in liver is____________?

A: UTP B: GTP C: Pyruvate Kinase D: Guanosine

Q49 : HMP shunt is of great importance in cellular metabolism because its produces_____________?

A: ATP B: ADP C: Acetyl CoA D: NADPH

Q50 : Triglyceride synthesis synthesis is increased by______________?

A: Growth hormone B: Insulin C: Cortisol D: Gulcagon

Q51 : Genes are_____________?

A: Ribonucleic acid B: Deoxy ribonucleic acid C: Lipoproteins D: Chromo proteins

Q52 : Which of the following amino acid is involved in gluconeogenesis______________?

A: Glycine B: Valine C: Cysteline D: All of the above

Q53 : Most lipogenic____________?

A: Fructose B: Glucose C: Galactose D: Ribose

Q54 : Serum creatine kinase-3 (CK-3) is elevated in_______________?

A: Muscular dystrophy B: Myocardial infarction C: Alcoholic cirrhosis D: Brain tumours

Q55 : Adipose tissue releases free fatty acids in the________________?

A: Fasting state B: Resting state C: Active state D: All of the above

Q56 : Lipid is required in the average diet because it________________?

A: has a high caloric value B: Provides essential fatty acid C: aids in absorption of carbohydrates D: is necessary for storage of carbohydrates

Q57 : Which is not a oligosaccharide sugar ?

A: Galactose B: Lactose C: Maltose D: Sucrose

Q58 : The enzyme that is specifically increased in obstructive jaundice is_____________?

A: Glutamate oxaloacetate transaminase B: Glutamate pyruvate transaminase C: Alkaline phosphaase D: Acid phosphatase

Q59 : Enzymes involved in degradation of epinephrine_____________?

A: Cholinesterase B: Anticholinesterases C: Catechol 0-transferase D: Oxidases

Q60 : Which of these organelle functions as the digestive system of the cell ?

A: Mitochondria B: Rough endoplasmic reticulum C: Golgi apparatus D: Lysomes

Q61 : Unwinding of DNA is done by____________?

A: DNAse B: Topo isomerase C: Ligase D: Reverse transcriptase

Q62 : The deficiency of thiamine can be identified by measuring the red cell______________?

A: Transketaolase B: Transaldolase C: Alpha ketoglutarate dehydrogenase D: Pyruvate dehydrogenase

Q63 : A material that speeds up a chemical reaction without chemically becoming involved is called_____________?

A: A solvent B: A base C: A catalyst D: Thermoplastic

Q64 : The tissue with the highest glycogen content (mg/100gm)_____________?

A: Liver B: Muscle C: Kidneys D: Testes

Q65 : DNA double helix is bound by_____________?

A: Covalent bond B: Hydrogen bond C: Disulfide linkage D: Vander wall forces

Q66 : Fatty acid oxidation occurs in______________?

A: Cytoplasm B: Microsomes C: Mitochondria D: All of the above

Q67 : Km of an enzyme is_____________?

A: Dissociation constant B: The normal physiological substrate concentration C: Substrate concentration at half maximal velocity D: Numerically identical for all isozymes that catalyses a given reaction

Q68 : Increase in lactate and pyruvate is seen in deficiency of_____________?

A: Pyridoxin B: Niacin C: Thiamine D: Retinotic acid

Q69 : Fraction of CPK is an enzyme that is elevated in a myocardial infarct is____________________?

A: MM fraction B: MB fraction C: BB fraction D: Both MM and BB fraction

Q70 : All these reactions take place inside the mitochondria except____________?

A: EMP pathway B: Krebs cylce C: Urea cycle D: Electron transfer

Q71 : The amino acid residue having animino side chain is____________?

A: Lysine B: Histidine C: Tyrosine D: Proline

Q72 : The fastest moving fraction of protein in serum When subjected to paper electrophoresis is_____________?

A: Albumin B: Alpha 1 globulin C: Beta Globulin D: Gamma Globulin

Q73 : Hexokinase is a______________?

A: Transferase B: Reductase C: Oxidoreductase D: Oxidase

Q74 : The amino acid required for the synthesis of haem is______________?

A: Glutamine B: Glutamic acid C: Glycine D: Lysine

Q75 : Creatine is formed metabolically from______________?

A: Tryptophan B: Arginine C: Phenylalanine D: Histidine

Q76 : The immediate precursor of norepinephrine is______________?

A: Epinephrine B: Tyrosine C: Dopamine D: Phenylalanine

Q77 : Serum alkaline phosphatase level increase in_______________?

A: Hypothyroidism B: Carcinoma of prostate C: Hyperparathyroidism D: Myocardial infarction

Q78 : Which of the following is a membrane bound enzyme that catalyzes the formation of cyclic AMP from ATP ?

A: Tyrosine kinase B: Polymerase C: ATP synthase D: Adenylate cyclase

Q79 : Multiienzyme complex in human_______________?

A: Fatty acid synthetase B: Malonyl CoA carboxylase C: Carbomoyl Phosphate synthetase D: Adenosine phospho ribosyl transferase

Q80 : Nonsense codons bring about__________________?

A: Elongation of polypeptide chain B: Pre-translational modification of protein C: Initiation of protein synthesis D: Termination of protein synthesis

Q81 : The patient suffered from hypogondism, failure to thrive, lose of taste and unable to maintain stability. This shows the deficiency of_____________?

A: Zinc B: Chromium C: Copper D: Potassium

Q82 : Argentaffinoma is characterized by excess excretion of_____________?

A: 5- Hydroxy indole acetate B: 3- Hydroxy phenyl pyruvate C: Phenyl lactate D: Phenyl acetate

Q83 : Which is the poorest source of calcium among the following______________?

A: Rice B: Human milk C: Egg yolk D: Cow’s milk

Q84 : In which type of glycogen storage disease is hyper uricemia a feature ?

A: I B: II C: III D: IV

Q85 : The nitrogen content in 50 gm of a typical dietary protein is most likely to be_____________?

A: 5 gm B: . 8 gm C: 10 gm D: 16 gm

Q86 : In Cytochrome p450, P stands for____________?

A: Structural proteins B: Substrate protiens C: Pigment D: Polymer

Q87 : Normal serum calcium level is_______________?

A: . 4-6 mg/dl B: 9-11 mg/dl C: 19-21 mg/dl D: 20-30 mg/dl

Q88 : Free radicals can be inactivated by the following enzymes EXCEPT__________________?

A: Glutathione peroxidase B: Catalase C: Superoxide dismutase D: Myeloperoxidase

Q89 : Fructose intolerance is to_____________?

A: Fructose only B: Fructose and glucose C: Sucrose only D: Fructose and sucrose

Q90 : Insulin increase the following pathways in liver EXCEPT____________?

A: Fatty acid synthesis B: Glycogen synthesis C: Protein syntehsis D: Glucose synthesis

Q91 : An example of layses is_____________?

A: Glutamine synthetase B: Fumarase C: Cholinesterase D: Amylase

Q92 : R-RNA is mainly produced mainly in___________?

A: Nucleus B: Nucleolus C: Ribosome D: Endoplasmic reticulum

Q93 : Histidine is converted to histamine by_____________?

A: Transamination B: Hydroxylation C: Hydroxylation D: Reduction

Q94 : Enzymes increase reaction rates by______________?

A: Altering the free energy of the action B: Inhibiting the backward reaction C: Enhancing the forward reaction D: Decreasing the energy of activation

Q95 : The key enzyme of gluconeogenesis is______________?

A: Pyruvate carboxylase B: Fructose 1,6 disphosphatase C: Glucose 6 phosphatase D: Phosphoenol pyruvate carboxykinase

Q96 : The fluid mosaic model of membrane structure was proposed by_______________?

A: Watson and Crick B: Edwarg Angle C: G.V Black D: Singer and Nicolson

Q97 : Which of the following is not a second messenger ?

A: c AMP B: c GMP C: Phosphatidyl inosital D: Phosphatidyl glycerol

Q98 : Triglycerides in serum are transported by_______________?

A: HDL B: VLDL C: LDL D: Chylomicrons

Q99 : Which base is not found in DNA________________?

A: Adenine B: Guanine C: Cytosine D: Uracil

Q100 : Key enzyme in urea synthesis is____________? 0 A. Urease

A: Urease B: Carbamyl synthetase C: Arginase D: Ornithine

Free Biochemistry MCQs Mock Test Online with Answers

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