Free Biochemistry MCQs Mock Test Online with Answers

Q1 : ALbumin is synthesized by_____________?

A: Liver B: Kidney C: Muscle D: Spleen

Q2 : Most importent compansatory mechanism in metabolic acidosis______________?

A: Hyperventilation B: Increased NH3 excretion by kidneys C: Increased urinary phosphates D: Increased HCO3 Production

Q3 : What high energy phosphate compound is formed in the citric acid cycle through substrate level phosphorylation______________?

A: ATP B: TTP C: ITP D: GTP

Q4 : An enzyme that makes a double stranded DNA copy from a single stranded RNA template molecule is known as____________?

A: DNA polymerase B: RNA polymerase C: Reverse transcriptase D: Phospho kinase

Q5 : Cane sugar is____________?

A: Glucose B: Surose C: Fructose D: Maltose

Q6 : Alkaptonuria an inherited metabolic disorder is due to the deficiency of____________?

A: Homogentisate oxidase B: Cystathionase C: Pheylalanine hydroxylase D: Tyrosine transaminase

Q7 : An enzyme not involved in glycolysis is______________?

A: Enolase B: Phosphoglycero mutase C: Aldolase D: Glycerophosphate dehydrogenase

Q8 : Which of these is not included in parenteral therapy ?

A: Carbohydrates B: Fibres C: Fats D: Micronutrients

Q9 : Proteins are absorbed from GIT as_____________?

A: Amino acids B: Peptides C: Peptones D: All of the above

Q10 : The amino acid residue having animino side chain is____________?

A: Lysine B: Histidine C: Tyrosine D: Proline

Q11 : Which of the following amino acids is quickly converted to tyrosine ?

A: Arginine B: Glycine C: Phenylalanine D: Leucine

Q12 : Which of the following is false about starvation ketoacidosis ?

A: Metabolic acidosis B: Smell of acetone in breath C: Benedict’s test +ve D: Rothera’s test is +ve

Q13 : Urea is formed in_____________?

A: Brain B: Kidney C: Liver D: intestine

Q14 : Chargaff rule states that___________?

A: A+G=T+C B: A/T=G/C C: A=U=T=G=C D: A+T=G+C

Q15 : At PH 7 the binding of 2,3 DPG to hemoglobin occurs at which site ?

A: Sulphydryl group B: Carboxy terminal C: Amino terminal D: Histidine

Q16 : Lipid from tissue is carried to liver by_____________?

A: LDL B: VLDL C: HDL D: Chylomicrons

Q17 : True about prostaglandins is______________?

A: Short acting B: Present in many tissues C: Some require C-AMP for their action D: All are true

Q18 : The antibacterial substance present in tears which acts by splitting cell wall components is____________?

A: Penicillin B: Lysozyme C: Betalysine D: Lactoperoxidase

Q19 : End product of purine metabolism is______________?

A: Creatinine B: Uric acid C: Xanthine D: Phosphates

Q20 : Enzymes concerned with the citric acid cycle are found in______________?

A: Nucleus B: Mitochondria C: Ribosomes D: Non-particulate cytoplasm

Q21 : Ketone body formation takes place in_______________?

A: Liver B: Kidney C: Spleen D: Blood

Q22 : Enzymes increase reaction rates by______________?

A: Altering the free energy of the action B: Inhibiting the backward reaction C: Enhancing the forward reaction D: Decreasing the energy of activation

Q23 : Nonsense codons bring about__________________?

A: Elongation of polypeptide chain B: Pre-translational modification of protein C: Initiation of protein synthesis D: Termination of protein synthesis

Q24 : Gluconeogenesis occurs in the liver and _______?

A: Kidney B: Muscle C: Heart D: Fat

Q25 : Urea is produced by the enzyme_____________?

A: Urease B: Uricase C: Arginase D: Glutaminase

Q26 : Increase in lactate and pyruvate is seen in deficiency of_____________?

A: Pyridoxin B: Niacin C: Thiamine D: Retinotic acid

Q27 : Bile contains______________?

A: Cholic acid B: Chenodeoxycholic acid C: Lithocholic acid D: All of the above

Q28 : Which of the following is a derived a derived protein_____________?

A: Protamines B: Peptones C: Prolamines D: Lactalbumin

Q29 : Which is not seen in HMG CoA pathway ?

A: Pyruvate B: Cholesterol C: Mevalonate D: . Acetyl CoA

Q30 : The enzymes that catalyses the same reaction but differ in physical properties are called as_____________?

A: Pro enzyme B: Iso enzyme C: Co-enzyme D: Holoenzyme

Q31 : Renal threshold for glucose is______________?

A: 80 mg% B: 100 mg% C: 180 mg/ dl D: 200 mg%

Q32 : A mutation that converts an amino acid codon to a stop codon is a_____________?

A: Nonsense mutation B: Transversion C: Silent mutation D: Frame shift mutation

Q33 : Enzyme + coenzyme constitutes_____________?

A: Apoenzyme B: Proenzyme C: Protoenzyme D: Holoenzyme

Q34 : Ubiqultin is involved in_____________?

A: Intracellular proteolysis B: Electron transport chain C: Transport of ATP D: Protein folding

Q35 : Which of the following combination is correct ?

A: Thiamine – Acyl CoA B: Biotin-CO2 C: ATP-Hydrogen D: All of the above

Q36 : Argentaffinoma is characterized by excess excretion of_____________?

A: 5- Hydroxy indole acetate B: 3- Hydroxy phenyl pyruvate C: Phenyl lactate D: Phenyl acetate

Q37 : Type II glycogen storage disorder is due to deficiency of______________?

A: Alpha -Glucosidase B: Alpha galactosidase C: Muscle phosphorylase D: Acid Lipase

Q38 : Ketone bodies are by products of metabolism of_____________?

A: Carbohydrate B: Protein C: Fat D: All of the above

Q39 : Enzymes are classified according to_________________?

A: Action on substrate B: Action of coenzymes C: Nature of the enzymes D: All of the above

Q40 : Which of the following is inclusion of cytoplasm ?

A: Endoplasmic reticulum B: Ribosome C: Golgi body D: Glycogen

Q41 : Which of the following is a membrane bound enzyme that catalyzes the formation of cyclic AMP from ATP ?

A: Tyrosine kinase B: Polymerase C: ATP synthase D: Adenylate cyclase

Q42 : All are true regarding glucose 6 phosphate deficiency except______________?

A: Hyperuricemia B: Hyperglycemia C: Defective cori cycle D: Increased mobilization of glycogen from liver

Q43 : On complete hydrolysis of DNA we will get all the following except______________?

A: Deoxy pentose sugar B: Phosphoric acid C: Adenosine D: Purine bases

Q44 : A example of a preventive antioxidant is_______________?

A: Catalase B: Tocopherol C: Superoxide dismutase D: Urate

Q45 : Which of the following is not a part of hemoglobin molecule___________?

A: Pyrrole rings B: Vinyl groups C: Histidine D: Ferric ions

Q46 : The most abundant protein present in body is_____________?

A: Globulin B: Albumin C: Collagen D: Hemoglobin

Q47 : The following is not a carrier protein________________?

A: Cerruloplasmin B: Transferrin C: Transcobalamine D: Haptoglobulin

Q48 : Bile acids are formed from__________?

A: Cholesterol B: Aminoacids C: Bilirubin D: Lipoproteins

Q49 : Hyponatremia is defined as a serum Na+ level ____________________?

A: < 135 mmol/L B: . >135 mmol/L C: < 160 mmo/L D: < 100 mmo/L

Q50 : The conversion of glucose 6-P to fructose 6-P is an example of which of the following reactions___________?

A: Phosphate transfer B: Isomerisation C: Dehydration D: Aldol cleavage

Q51 : The normal level of serum cholesterol is_______________?

A: 100-140 mgs/100 ml B: 260-360 mgs/100 ml C: 150-250 mgs/100 ml D: 80-250 mgs/100 ml

Q52 : The main site of fluoride inhibition in the Embden Meyerhof pathway of acid____________?

A: ATPase B: Enolase C: Pyruvate Kinase D: Fructose 6 phosphatase

Q53 : In the physiological system, nitric oxide is known to act through_______________?

A: Cyclic AMP B: Calcium ions C: Cyclic GMP D: Prostacyclins

Q54 : The lipoprotein particles that have the highest percentage concentration of cholesterol is_______________?

A: Chylomicron B: VLDL (Very low density lipoprotein) C: VLDL (Very low density lipoprotein) D: HDL (High density lipoprotein)

Q55 : The rate of absorption of sugars by the small intestine is highest for_______________?

A: Pentoses B: Disaccharides C: Polysaccharides D: Hexoses

Q56 : The major fuel for the brain after several weeds of starvation______________?

A: Glucose B: Fatty acid C: Beta hydroxy butyrate D: Glycerol

Q57 : Inactive precursors of enzymes are known as_______________?

A: Apoenzymes B: Coenzymes C: Proenzymes D: Holoenzymes

Q58 : Bilirubin is produced from________________?

A: Haemoglobin B: Myoglobin C: Gall bladder D: A & B

Q59 : A patient of type 2 diabetes mellitus is given nutrition rich in________________?

A: Proteins B: Carbohydrates C: . Fat D:

Q60 : Which of the following is not a second messenger ?

A: c AMP B: c GMP C: Phosphatidyl inosital D: Phosphatidyl glycerol

Q61 : The enzyme phosphofructo kinase-1 is strongly activated by_______________?

A: Cyclic AMP B: Adenosine tri phosphate C: Citrate D: Fructose 2,6 bis phosphate

Q62 : In which type of glycogen storage disease is hyper uricemia a feature ?

A: I B: II C: III D: IV

Q63 : If bile acid recycling time is short, then bile salt reservoir pool will be______________?

A: Increased B: Decreased C: Uchanged D: Has no effect

Q64 : Kreb’s cycle occurs in _________ conditions?

A: Aerobic B: Anaerobic C: Anaerobic D: Aerobic and anaerobic

Q65 : Which of the following is a precursor of protoporphyrin_______________?

A: Alanine B: Leucine C: Histidine D: Glycine

Q66 : Which of the following is NOT a characteristic feature of allosteric enzymes ?

A: They are multienzyme complex B: Follow Michaelis-Menton Kinetics C: Presence of Modulator site D: Give sigmoid shaped curve

Q67 : Glutamine replaced by valine in sckle cell anaemia is characterized________________?

A: Non Sense mutation of beta chain B: Missense mutation of beta chain C: Degradation of beta chain D: Deletion of beta chain

Q68 : Non essential amino acids are not_____________?

A: Used by the body B: Forming part of the proteins C: Required in the diet D: Absorbed in the intestines

Q69 : In TCA cycle, citrate is converted in to after losing a molecule of H2O_____________?

A: Isocitrate B: Cisaconitate C: Oxalocetate D: Glutarate

Q70 : Peroxidase enzyme contain______________?

A: Chromium B: Selenium C: Magnesium D: Calcium

Q71 : Amino acids excreted in the urine in cystinosis______________?

A: Cystine B: Ornithine C: Lysine D: All of the above

Q72 : In glycolysis ATP is produced by the following enzyme______________?

A: Hexokinase B: Phosphoglycerate kinase C: Enolase D: Phosphohexose isomerase

Q73 : The reducing equivalent for fatty acid synthesis is derived form____________?

A: Glycolysis B: Kreb’s cycle C: Urea cycle D: Pentose phosphate pathway

Q74 : Detoxification of drugs is controlled by_____________?

A: Cytochrome B: Cytochrome P450 C: Cytochrome C D: Cytochrome A

Q75 : Which of the following fatty acids are not syntehsised in human body____________

A: . Oleic, linoleic and linolenic acid B: Arachidonic, linolenic and linoleic acid C: Palmitic Oleic and arachidonic D: Linoleic, arachidonic and stearic acid

Q76 : The best technique useful for initial viral load estimation is________________?

A: Real time PCR B: Widal test C: Electrophoresis D: Immunofluoresence

Q77 : Enzymes help by____________?

A: Lowering the activation energy B: Increasing the substrate concentration C: Decreasing the surface tension D: Increasing the activation energy

Q78 : LDH has following number oflsoenzymes________________?

A: 5 B: 3 C: 11 D: 2

Q79 : True about G protein couple receptors is _________________ ?

A: G proteins bind to hormones on the cell surface B: All the three subunits alpha, beta and gamma should bind each other for G protein to act C: G Proteins act as inhibitory and excitatory because of difference in alpha subunit D: G protein is bound to GTP in resting state

Q80 : Inside the cell, the substance, which contributes to most of the osmolality, is________________?

A: Protein B: Potassium C: Urea D: Phosphate

Q81 : Unsaturated fatty acids are converted to______________?

A: Prostaglandins B: Cholesterol C: Cell membrane lipid D: Saturated fatty acid

Q82 : The most important buffer in RBC is____________?

A: O2 Hb +Na hemoglobinate B: O2Hb +K hemoglobinate C: H2CO3 + KHCO3 D: H2CO3 +NAHCO3

Q83 : Codons are present on_____________?

A: m-RNA B: DNA C: t-RNA D: Ribosomal RNA

Q84 : Hydroxylation of proline require the following except____________?

A: Fe+2 B: O2 C: Ascorbic acid D: Succinate

Q85 : The key enzyme of gluconeogenesis is______________?

A: Pyruvate carboxylase B: Fructose 1,6 disphosphatase C: Glucose 6 phosphatase D: Phosphoenol pyruvate carboxykinase

Q86 : The abundant glycoprotein in the basement membrane and has binding domain for both ECM and cell-surface receptor is______________?

A: Laminin B: Fibronectin C: E – Cadherins D: Tenascin

Q87 : Blood glucose level cannot be augmented by mobilization of muscle glycogen due to lack of_____________?

A: G-6-P dehydrogenase B: G-6-P phydrogenase C: Aldolase D: Glucokinase

Q88 : The ketone bodies, which are excreted in diabetic ketoacidosis ?

A: Acetoacetic acid and pyruvic acid B: Acetoacetic acid and oxalocacetic acid C: Acetoacetic acid and alpha ketoglutaric acid D: Acetoacetic acid and beta hydroxyl butyric acid

Q89 : All of the following are substrates for gluconeogenesis except_______________?

A: Alanine B: Oleic acid C: Glycerol D: Tryptophan

Q90 : An example of layses is_____________?

A: Glutamine synthetase B: Fumarase C: Cholinesterase D: Amylase

Q91 : Elevated levels of serum glutamic oxaloacetic transaminase in indicative of______________?

A: Deficiency of glutamic acid B: Deficiency of oxaloacetic acid C: Liver disease D: All of the above

Q92 : Which metabolite of TCA cycle is used in detoxification of ammonia in brain_____________?

A: Alpha ketoglutarate B: Ornithine C: Oxalocetate D: Oxalocetate

Q93 : Major source of ammonia in the kidney is___________?

A: Urea Aspartate B: Aspartate C: Glutamine D: Glutamate

Q94 : Lipid is required in the average diet because it________________?

A: has a high caloric value B: Provides essential fatty acid C: aids in absorption of carbohydrates D: is necessary for storage of carbohydrates

Q95 : Ribosomes are usually associated with______________?

A: Endoplasmic reticulum B: Mitochondria C: Nucleolus D: Plasma membrane

Q96 : In Hartnup’s disease _______ is excreted in the urine?

A: Ornithine B: Glutamine C: Tryptophan D: Phenylalanine

Q97 : The precursor of cholesterol synthesis is________________?

A: Acetic acid B: Acetyl CoA C: Oxalo acetic acid D: Pyruvate

Q98 : Decarboxylation of which of the following amino acids results in formation of a vasodilator ?

A: Valine B: Arginine C: Histidine D: Glutamic acid

Q99 : The main function of mitochondria is______________?

A: Protein synthesis B: Oxidation C: Electron transfer D: Fat synthesis

Q100 : Coenzyme, in an enzymatic reaction usually functions to_____________?

A: Activate the substrate B: Increase the active sites of apoenzyme C: Enhance the specificity of apoenzyme D: Accept one of the cleavage products

Free Biochemistry MCQs Mock Test Online with Answers

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