Free Biochemistry MCQs Mock Test Online with Answers

Q1 : Non essential amino acids are not_____________?

A: Used by the body B: Forming part of the proteins C: Required in the diet D: Absorbed in the intestines

Q2 : Coenzyme responsible for single carbon transfer is______________?

A: Acetyl co enzyme A B: Biotin C: THF4 D: Pyridoxine

Q3 : The rate of absorption of sugars by the small intestine is highest for_______________?

A: Pentoses B: Disaccharides C: Polysaccharides D: Hexoses

Q4 : The product of oxidation of odd chainfatty acids is______________?

A: Aceto acetyl CoA B: Malonyl CoA C: Propionyl CoA D: Fumaryl CoA

Q5 : B-oxidation of odd-chain fatty aids produce_______________?

A: Succinyl CoA B: Propionyl CoA C: Acetyl CoA D: Malonyl CoA

Q6 : The main site of fluoride inhibition in the Embden Meyerhof pathway of acid____________?

A: ATPase B: Enolase C: Pyruvate Kinase D: Fructose 6 phosphatase

Q7 : Which of the following is not a polymer of glucose?

A: Glycogen B: Cellulose C: Amylase D: Inulin

Q8 : Daily requirement of iron in man is_____________?

A: 1gm B: 10 microgram C: 10 mg D: 20 mg

Q9 : Enzyme + coenzyme constitutes_____________?

A: Apoenzyme B: Proenzyme C: Protoenzyme D: Holoenzyme

Q10 : The first product of glycogenolysis is_____________?

A: Glucose 6 phosphatase B: Glucose 1,6 diphosphatase C: Glucose 1- phosphatase D: Fructose 1- phosphatase

Q11 : The combination of main supporting enzyme is called______________?

A: Apoenzyme B: Coenzyme C: Holoenzyme D: Constitutive enzyme

Q12 : The normal range of serum osmolality (in mosm/L) is_____________?

A: 280 to 295 B: 300 to 320 C: 350 to 375 D: 200 to 250

Q13 : Glucose 6 phosphatase deficiency is seen in______________?

A: Pomper’s disease B: Von Gierke’s disease C: McArdles syndrome D: Downs syndrome

Q14 : Muscle glycogen, which cannot contribute to blood glucose due to the absence of which enzymes ?

A: Phosphoglutamase B: Branching enzyme C: Debranching enzyme D: Glucose-6-phosphotase

Q15 : The main enzyme responsible for activation of xenobiotics in (detoxification)____________?

A: Cytochrome P-450 B: Glutathione S-transferase C: NADPH cytochrome P-450 reductase D: Glucuronyl transferase

Q16 : Which one of the following human tissues contains the greatest amount of body glycogen ?

A: Liver B: Kidney C: Skeletal muscle D: Cardiac muscle

Q17 : The normal value of serum potassium level is____________?

A: 2.8-3.8 meq/L B: 3.8-5 meq/L C: 5-5.8 meq/L D: 6-7.2 meq/L

Q18 : Which acid is formed in the citric acid cycle ?

A: Oxaloacetic acid B: Glutamic acid C: Nitric acid D: None of the above

Q19 : LDH has following number oflsoenzymes________________?

A: 5 B: 3 C: 11 D: 2

Q20 : The most important buffer in RBC is____________?

A: O2 Hb +Na hemoglobinate B: O2Hb +K hemoglobinate C: H2CO3 + KHCO3 D: H2CO3 +NAHCO3

Q21 : Rate limiting step in cholesterol synthesis is_______________?

A: HMG CoA synthetase B: HMG CoA lyase C: HMG CoA reductase D: Mevalonate synthetase

Q22 : Acetyl Co-A acts as a substrate for all the enzymes except______________?

A: HMG-Co A synthase B: Malic enzyme C: Malonyl CoA synthetase D: Fatty acid synthetase

Q23 : The compound that can give rise to glucose by gluconeogenesis is_____________?

A: Acetyl CoA B: Lactate C: Palmitic acid D: Fructose

Q24 : The abundant glycoprotein in the basement membrane and has binding domain for both ECM and cell-surface receptor is______________?

A: Laminin B: Fibronectin C: E – Cadherins D: Tenascin

Q25 : Normal serum calcium level is_______________?

A: . 4-6 mg/dl B: 9-11 mg/dl C: 19-21 mg/dl D: 20-30 mg/dl

Q26 : Which of the following is inclusion of cytoplasm ?

A: Endoplasmic reticulum B: Ribosome C: Golgi body D: Glycogen

Q27 : Type II glycogen storage disorder is due to deficiency of______________?

A: Alpha -Glucosidase B: Alpha galactosidase C: Muscle phosphorylase D: Acid Lipase

Q28 : Kreb’s cycle does not occur in______________?

A: Muscle B: RBC C: Heart D: All of the above

Q29 : Ferritin – an inactive form of iron is stored in_____________?

A: Gut B: Spleen C: Liver D: All of the above

Q30 : Calcitonin is antagonist_______________?

A: Parathyroid hormone B: Thyroxine C: Triidothyronine D: Serotonin

Q31 : Rate limiting step in adrenaline synthesis is conversion of____________?

A: Tyrosine to dopa B: Phenylalanine to tyrosine C: Dopa to dopamine D: Dopamine to nor epinephrine

Q32 : The amino acid residue having animino side chain is____________?

A: Lysine B: Histidine C: Tyrosine D: Proline

Q33 : The most abundant protein present in body is_____________?

A: Globulin B: Albumin C: Collagen D: Hemoglobin

Q34 : The activity of the following enzyme is affected by biotin deficiency____________?

A: Transketolase B: Dehydrogenase C: Oxidase D: Carboxylase

Q35 : Dehydrogenase used as coenzymes all of the following, except________________?

A: FMN B: FAD C: NADP+ D: Ferro protoporphyrin

Q36 : All are true about glutathione except ?

A: It conjugates xenobiotics B: It is a tripetide C: It converts hemoglobin to methemoglobin D: It scavenges free radicals and superoxide ions

Q37 : Ketone bodies are normally synthesized from______________?

A: Acetyl-CoA B: Glucose C: Glycerol D: Acetone

Q38 : Phosphofructokinase is the key enzyme of______________?

A: Glycolysis B: Gluconeogenesis C: Gluconeogenesis D: TCA cycle

Q39 : The sugar component of cerebrosides is_____________?

A: Fructose B: Sucrose C: Galactose D: None of the above

Q40 : Mannose 6 phosphate containing freshly synthesized proteins are directed to_____________?

A: Nucleus B: Lysosomes C: Mitochondria D: Golgi apparatus

Q41 : Glycine is present in____________?

A: Hemoglobin B: Glutathione C: Creatine D: All of the above

Q42 : An enzyme not involved in glycolysis is______________?

A: Enolase B: Phosphoglycero mutase C: Aldolase D: Glycerophosphate dehydrogenase

Q43 : Which of the following combination is correct ?

A: Thiamine – Acyl CoA B: Biotin-CO2 C: ATP-Hydrogen D: All of the above

Q44 : Oligosaccharide is________________?

A: Glucose B: Gructose C: Maltose D: Dextrin

Q45 : The main pathway for De – Novo synthesis of fatty acids occurs in_______________?

A: Mitochondria B: Nucleus C: Cytosol D: None of the above

Q46 : The sigma subunit of prokaryotic RNA polymerase_______________?

A: Binds the antibiotic Rifampicin B: Is inhibited by a-amanitin C: Specifically recognizes the promoter site D: Is part of the core enzyme

Q47 : Cane sugar is____________?

A: Glucose B: Surose C: Fructose D: Maltose

Q48 : HMG-CoA is formed during metabolism of all except______________?

A: Cholesterol B: Leucine C: Ketone bodies D: Bile acids

Q49 : Kreb’s cycle occurs in _________ conditions?

A: Aerobic B: Anaerobic C: Anaerobic D: Aerobic and anaerobic

Q50 : An enzyme that makes a double stranded DNA copy from a single stranded RNA template molecule is known as____________?

A: DNA polymerase B: RNA polymerase C: Reverse transcriptase D: Phospho kinase

Q51 : Cholesterol levels in abnormal person should be preferably less than_____________?

A: 200 mg/dl B: 180 mg/dl C: 150 mg/dl D: 120 mg/dl

Q52 : Insulin increase the following pathways in liver EXCEPT____________?

A: Fatty acid synthesis B: Glycogen synthesis C: Protein syntehsis D: Glucose synthesis

Q53 : Enzymes concerned with the citric acid cycle are found in the____________?

A: Nucleus B: Ribosomes C: Mitochondria D: Nonparticulate cytoplasm

Q54 : Ubiqultin is involved in_____________?

A: Intracellular proteolysis B: Electron transport chain C: Transport of ATP D: Protein folding

Q55 : Which of the following is not a ketone body______________?

A: Acetone B: Acetic acid C: Acetocetate D: Beta hydroxybutyric acid

Q56 : Saponification means hydrolysis of fats by________________?

A: Acid B: Alkali C: Water D: Enzymes

Q57 : Which of the following is the best site of absorption of calcium ?

A: Proximal segment of small intestine B: Middle segment of small intestine C: Ascending colon D: Ileum

Q58 : Iron is complexed in haemoglobin to_______________?

A: Leucine B: Histidine C: Isoleucine D: Valine

Q59 : The uptake of glucose by the liver increase following a carbohydrate meal because____________?

A: There is increase in phosphorylation of glucose by glucokinase B: GLUT-2 stimulated by insulin C: Glucokinase has a low Km for glucose D: Hexokinase in liver has a high affinity for glucose

Q60 : False statement about haemoglobin structure________________?

A: False statement about haemoglobin structure________________? B: Iron is present in ferrous state C: Hb structurally similar to myoglobin D: Ferrous ions are in porphyrin rings

Q61 : Detoxification or protective synthesis occurs by____________?

A: Oxidation B: Reduction C: Conjugation D: Any of the above

Q62 : Decarboxylation of which of the following amino acids results in formation of a vasodilator ?

A: Valine B: Arginine C: Histidine D: Glutamic acid

Q63 : Quaternary structure of protein is_____________?

A: The arrangement sequence of amino acids in the polypeptide chain B: Inter relation between amino acids in a single polypeptide chain C: Inter relation of amino acids in 2 polypeptide chains D: The inter relation and arrangement of polypeptides in a protein with more than 2 polypeptide chains

Q64 : Which of the following is correctly matched ?

A: Isocitrate to oxalo succinate -1 ATP is formed B: Succinyl CoA to succinate -1 ATP is formed C: Succinate to furmarate -1 ATP is formed D: Succinate to furmarate -1 ATP is formed

Q65 : Synthesis of protein occurs on__________________?

A: Mitochondria B: Poly ribosomes C: Nucleus D: Golgi bodies

Q66 : Iron is present in all, EXCEPT______________?

A: Myoglobin B: Cytochrome C: Catalase D: Pyruvate kinase

Q67 : Galactosemia commonly is due to deficiency of_____________?

A: Galactose 1 phosphatase uridyl transferase B: Galactose 1 phosphatase C: Glucose 1 phosphatase D: Glucose 6 phosphatase

Q68 : Which of the following is most important content of diet ?

A: Protein B: Water C: Vitamin D: Minerals

Q69 : In glycolysis ATP is produced by the following enzyme______________?

A: Hexokinase B: Phosphoglycerate kinase C: Enolase D: Phosphohexose isomerase

Q70 : Ketone bodies are by products of metabolism of_____________?

A: Carbohydrate B: Protein C: Fat D: All of the above

Q71 : The citric acid cycle is the final pathway for oxidation of______________?

A: Enzymes B: Enzymes C: Minerals D: None of the above

Q72 : In which type of glycogen storage disease is hyper uricemia a feature ?

A: I B: II C: III D: IV

Q73 : Increase in pyruvate and lactate is seen in which of the following deficiency ?

A: Thiamine B: Pyridoxine C: Niacin D: Vitamin C

Q74 : Which of the following is not a part of hemoglobin molecule___________?

A: Pyrrole rings B: Vinyl groups C: Histidine D: Ferric ions

Q75 : End product of purine metabolism is______________?

A: Creatinine B: Uric acid C: Xanthine D: Phosphates

Q76 : The main function of HDL is____________?

A: Transport cholesterol from liver to peripheral tissues B: Esterification with PUFA C: Both of the above D: None of the above

Q77 : Ligant for peroxisome proliferation activating receptor (PPAR) receptors, a group of nuclear hormone receptors that are involved in the regulation of genes related to glucose and lipid metabolism is_____________?

A: Repaglinide B: Repaglinide C: Repaglinide D: Repaglinide

Q78 : In molecular cloning, Blue White screening is used for_______________?

A: To screen for recombinant vectors B: To detect gene mutations C: To identify desired chromosomal DNA insert in plasmid vectors D: To detect host DNA in situ

Q79 : Which of the following is a function of the golgi apparatus ?

A: Modification of proteins B: m RNA synthesis C: Protein storage D: t RNA synthesis

Q80 : Step in HMP pathway requiring TPP_____________?

A: G6 PD B: 6 phosphogluconate dehydrogenase C: Transketolase D: Transaldolase

Q81 : During phagocytosis the metabolic process called respiratory burst involves activation of_____________?

A: Oxidase B: Hydrolase C: Peroxidase D: Dehydrogenase

Q82 : Heme is converted to bilirubin mainly in_____________?

A: Kidney B: Liver C: Spleen D: Bone marrow

Q83 : In prolonged starvation the main nergy source of brain is_____________?

A: Glucose B: Ketone bodies C: Fructose D: Fatty acids

Q84 : The most important role of cholesterol is_____________?

A: It is a component of cell membrane B: It is a precursor of polyunsaturated fatty acids C: It stores up energy D: None of the above

Q85 : Golgi bodies function are______________?

A: Protein lipid synthesis B: Protein synthesis C: Sorting of glycoproteins D: None of the above

Q86 : Which of the organelles contain DNA_________________?

A: Nucleus B: Golgi apparatus C: Nucleolus D: Golgi apparatus

Q87 : In TCA cycle or tricarboxylic acid cycle, which is first formed________________?

A: Isocitrate B: Citrate C: Succinate D: Fumarate

Q88 : Which metabolite of TCA cycle is used in detoxification of ammonia in brain_____________?

A: Alpha ketoglutarate B: Ornithine C: Oxalocetate D: Oxalocetate

Q89 : Enzymes concerned with the citric acid cycle are found in______________?

A: Nucleus B: Mitochondria C: Ribosomes D: Non-particulate cytoplasm

Q90 : Which of the following organs cannot use ketone bodies_______________?

A: Brain B: Liver C: Kidney D: Spleen

Q91 : Mutation in the oxidative enzymes (peroxisomes) could lead to_______________?

A: Zellweger’s syndrome B: Zellweger’s syndrome C: Epidermolysis bullosa D: Leber’s neuropathy

Q92 : Chargaff rule states that___________?

A: A+G=T+C B: A/T=G/C C: A=U=T=G=C D: A+T=G+C

Q93 : Inside the cell, the substance, which contributes to most of the osmolality, is________________?

A: Protein B: Potassium C: Urea D: Phosphate

Q94 : Which of the following is correct about breakdown of hemoglobin (Hb)_____________?

A: Hb→Heme→bilirubin→Urobilinogen B: Heme→Hb→Biliverdin→Urobilinogen C: Hb→Heme→Bilverdin→Uro bilinogen D: Hb→Heme→bilirubin→Urobilinogen→Biliverdin

Q95 : The amino acid, which is used is the estimation of collagen is_____________?

A: Hydroxyproline B: Proline C: Lysine D: Glycine

Q96 : Prostaglandin synthesis is partially switched off by______________?

A: Lipo oxygenase inhibition B: Cyclo-oxygenase inhibition C: Reductase D: Reductase

Q97 : In all the following RNA participates directly except________________?

A: Post translation modification B: Post transcriptional modification C: DNA replication D: Splicing

Q98 : Normal blood bilirubin level is______________?

A: 0.5 – 1 mg% B: 1 – 3 mg% C: 3 – 4 mg% D: 4 – 5.5 mg%

Q99 : Competitive enzyme inhibition will cause_____________?

A: Decrease of km and increase of Vmax B: increase of km and increase of Vmax C: Decrease of km and decrease of Vmax D: Increase of km and Unchanged of Vmax

Q100 : An essential for the conversion of glucose to glycogen in liver is____________?

A: UTP B: GTP C: Pyruvate Kinase D: Guanosine

Free Biochemistry MCQs Mock Test Online with Answers

Time to prove what you know!

LAT Test

GAT Test

Contact Info

Free Biochemistry MCQs Mock Test Online with Answers

Subscribe our Newsletter

LAT Test

GAT Test

Contact Info