Free Biochemistry MCQs Mock Test Online with Answers

Q1 : Which of the following is a phospholipid________________?

A: Glycogen B: Sphingomyelin C: Prostaglandin D: Oleic acid

Q2 : The main pathways of metabolism in brain are______________?

A: Glycolysis and citric acid cycle B: Glycogenolysis and Gluconeogenesis C: Embden-Meyerhof Pathway and H.M.P shunt D: Glycogenolysis and Citric and cycle

Q3 : Galactosemia commonly is due to deficiency of_____________?

A: Galactose 1 phosphatase uridyl transferase B: Galactose 1 phosphatase C: Glucose 1 phosphatase D: Glucose 6 phosphatase

Q4 : True about prostaglandins is______________?

A: Short acting B: Present in many tissues C: Some require C-AMP for their action D: All are true

Q5 : Glucose 6 phosphatase deficiency is seen in______________?

A: Pomper’s disease B: Von Gierke’s disease C: McArdles syndrome D: Downs syndrome

Q6 : Urea is formed in_____________?

A: Brain B: Kidney C: Liver D: intestine

Q7 : The normal value of serum potassium level is____________?

A: 2.8-3.8 meq/L B: 3.8-5 meq/L C: 5-5.8 meq/L D: 6-7.2 meq/L

Q8 : LDH has following number oflsoenzymes________________?

A: 5 B: 3 C: 11 D: 2

Q9 : End product of purine metabolism is______________?

A: Creatinine B: Uric acid C: Xanthine D: Phosphates

Q10 : Which of the following is precursor of adrenaline and thyroxine synthesis ?

A: Phenyl alanine B: Tyrosine C: Tryptophan D: None of the above

Q11 : The main enzyme responsible for activation of xenobiotics in (detoxification)____________?

A: Cytochrome P-450 B: Glutathione S-transferase C: NADPH cytochrome P-450 reductase D: Glucuronyl transferase

Q12 : The end product of glycolysis under anaerobic conditions is_______________?

A: Lactic acid B: Pyruvic acid C: Acetoacetic acid D: Oxaloacetic acid

Q13 : Which one of the following human tissues contains the greatest amount of body glycogen ?

A: Liver B: Kidney C: Skeletal muscle D: Cardiac muscle

Q14 : The major fuel for the brain after several weeds of starvation______________?

A: Glucose B: Fatty acid C: Beta hydroxy butyrate D: Glycerol

Q15 : Dietary fibre is rich in_____________?

A: Starch B: Cellulose C: Collagen D: Inulin

Q16 : Heme is converted to bilirubin mainly in_____________?

A: Kidney B: Liver C: Spleen D: Bone marrow

Q17 : Peroxidase enzyme contain______________?

A: Chromium B: Selenium C: Magnesium D: Calcium

Q18 : The uptake of glucose by the liver increase following a carbohydrate meal because____________?

A: There is increase in phosphorylation of glucose by glucokinase B: GLUT-2 stimulated by insulin C: Glucokinase has a low Km for glucose D: Hexokinase in liver has a high affinity for glucose

Q19 : In prolonged starvation the main nergy source of brain is_____________?

A: Glucose B: Ketone bodies C: Fructose D: Fatty acids

Q20 : Denaturation of double stranded DNA involves_______________?

A: It gets broken down to nucleotides B: It becomes single stranded reversibly C: It becomes single stranded irreversibly D: It becomes double stranded irreversibly

Q21 : The primary role of chaperones is to help in______________?

A: Protein synthesis B: Protein degradation C: Protein denaturation D: Protein folding

Q22 : Hyponatremia is defined as a serum Na+ level ____________________?

A: < 135 mmol/L B: . >135 mmol/L C: < 160 mmo/L D: < 100 mmo/L

Q23 : A small Ca+2 binding protein that modifies the activity of many enzymes and other proteins in response to changes of Ca+2 concentration is known as______________?

A: Cycline B: Calmodulin C: Collagen D: Kinesin

Q24 : Which of the following is not a second messenger ?

A: c AMP B: c GMP C: Phosphatidyl inosital D: Phosphatidyl glycerol

Q25 : Increase in lactate and pyruvate is seen in deficiency of_____________?

A: Pyridoxin B: Niacin C: Thiamine D: Retinotic acid

Q26 : In human body which of the following trace element is next to iron_______________?

A: Ca++ B: Zn++ C: Cu++ D: Selenium

Q27 : Colloidal osmotic pressure of plasma is by___________?

A: Albumin B: Fibrinogen C: Globulin D: Prothrombin

Q28 : Inhibition of glycolysis by O2 is known a_____________?

A: Muni effect B: Pasteur effect C: Hill reaction D: Gluconeogenesis

Q29 : One of the earliest symptoms of Vit. A deficiency is________________?

A: Nyctalopia B: Xerophthalmia C: Bitot’s spot D: Keratomalacia

Q30 : The antibacterial substance present in tears which acts by splitting cell wall components is____________?

A: Penicillin B: Lysozyme C: Betalysine D: Lactoperoxidase

Q31 : Kinase requires_______________?

A: MN++ B: Cu++ C: Mg++ D: Inorganic phosphate

Q32 : Proteins are linear polymers of amino acids, They fold into compact structures Sometimes these folded structures associate to form homo or hetero dimers Which one of the following refers to this associated form ?

A: Denatured state B: Molecular aggregation C: Precipitation D: Quaternary structure

Q33 : True about G protein couple receptors is _________________ ?

A: G proteins bind to hormones on the cell surface B: All the three subunits alpha, beta and gamma should bind each other for G protein to act C: G Proteins act as inhibitory and excitatory because of difference in alpha subunit D: G protein is bound to GTP in resting state

Q34 : Codons are present on_____________?

A: m-RNA B: DNA C: t-RNA D: Ribosomal RNA

Q35 : NADPH is required for________________?

A: Gluconeogenesis B: Glycolysis C: Fatty acid synthesis D: Glycogenolysis

Q36 : The fastest moving fraction of protein in serum When subjected to paper electrophoresis is_____________?

A: Albumin B: Alpha 1 globulin C: Beta Globulin D: Gamma Globulin

Q37 : The total blood concentration of ketone bodies in well fed individual is__________?

A: 1 mg% B: 5 mg% C: 12 mg% D: 20 mg%

Q38 : Which of the following is used in recombinant DNA technology ?

A: Restriction endonucleases B: PCR C: Reverse transcriptase FISH D: None of these

Q39 : Fat provides ______% of body’s calories?

A: 40% B: 30% C: 50% D: 75%

Q40 : The main function of HDL is____________?

A: Transport cholesterol from liver to peripheral tissues B: Esterification with PUFA C: Both of the above D: None of the above

Q41 : The rate of absorption of sugars by the small intestine is highest for_______________?

A: Pentoses B: Disaccharides C: Polysaccharides D: Hexoses

Q42 : Under metabolic conditions associated with a high rate of fatty acid oxidation liver produces________________?

A: Glutamate B: . Acetoacetate C: Cholesterol D: Glycine

Q43 : Normal blood bilirubin level is______________?

A: 0.5 – 1 mg% B: 1 – 3 mg% C: 3 – 4 mg% D: 4 – 5.5 mg%

Q44 : Unwinding of DNA is done by____________?

A: DNAse B: Topo isomerase C: Ligase D: Reverse transcriptase

Q45 : All are true about glutathione except ?

A: It conjugates xenobiotics B: It is a tripetide C: It converts hemoglobin to methemoglobin D: It scavenges free radicals and superoxide ions

Q46 : Kreb’s cycle occurs in _________ conditions?

A: Aerobic B: Anaerobic C: Anaerobic D: Aerobic and anaerobic

Q47 : Hexokinase is a______________?

A: Transferase B: Reductase C: Oxidoreductase D: Oxidase

Q48 : Which of them is multienzyme complex_____________?

A: Pyruvate dehydrogenase B: Pyruvate dehydrogenase C: Succinate dehydrogenase D: Both A & B

Q49 : Which of the organelles contain DNA_________________?

A: Nucleus B: Golgi apparatus C: Nucleolus D: Golgi apparatus

Q50 : Hydroxylation of proline require the following except____________?

A: Fe+2 B: O2 C: Ascorbic acid D: Succinate

Q51 : The precursor of steroid is_______________?

A: Amino acids B: Fatty acids C: Cholesterol D: None of the above

Q52 : Unsaturated fatty acids are converted to______________?

A: Prostaglandins B: Cholesterol C: Cell membrane lipid D: Saturated fatty acid

Q53 : In Cytochrome p450, P stands for____________?

A: Structural proteins B: Substrate protiens C: Pigment D: Polymer

Q54 : Enzymes involved in degradation of epinephrine_____________?

A: Cholinesterase B: Anticholinesterases C: Catechol 0-transferase D: Oxidases

Q55 : An enzyme that makes a double stranded DNA copy from a single stranded RNA template molecule is known as____________?

A: DNA polymerase B: RNA polymerase C: Reverse transcriptase D: Phospho kinase

Q56 : 1 molelcule of glucose forms _______ molecules of pyruvate?

A: 1 B: 2 C: 3 D: 4

Q57 : Chargaff rule states that___________?

A: A+G=T+C B: A/T=G/C C: A=U=T=G=C D: A+T=G+C

Q58 : Enzymes help by____________?

A: Lowering the activation energy B: Increasing the substrate concentration C: Decreasing the surface tension D: Increasing the activation energy

Q59 : Normal serum alkaline phosphatase level is_____________?

A: 100-400 Bodansky units B: 1000-4000 Bodansky units C: 0.1-0.4 Bodansky units D: 1-4 Bodansky units

Q60 : Normal serum calcium level is_______________?

A: . 4-6 mg/dl B: 9-11 mg/dl C: 19-21 mg/dl D: 20-30 mg/dl

Q61 : McArdles disease is due to the deficiency of_____________?

A: Glucose 1 phosphatase B: Glucose 1,6 phosphatase C: Glucose 6 phosphatase D: Myophosphorylase

Q62 : The number of essential amino acid are______________?

A: 6 B: 8 C: 12 D: 16

Q63 : Number of ATP molecules generated in the conversion of glycogen of lactate is_____________?

A: 2 B: 36 C: 38 D: 32

Q64 : Enzymes increase reaction rates by______________?

A: Altering the free energy of the action B: Inhibiting the backward reaction C: Enhancing the forward reaction D: Decreasing the energy of activation

Q65 : Enzyme + coenzyme constitutes_____________?

A: Apoenzyme B: Proenzyme C: Protoenzyme D: Holoenzyme

Q66 : Amino acids excreted in the urine in cystinosis______________?

A: Cystine B: Ornithine C: Lysine D: All of the above

Q67 : Normal level of serum phosphorous is_____________?

A: 2.5 – 4.5 mgm% B: 7-9 mgm% C: 40-50 mgm% D: 1-2 mgm%

Q68 : Km of an enzyme is_____________?

A: Dissociation constant B: The normal physiological substrate concentration C: Substrate concentration at half maximal velocity D: Numerically identical for all isozymes that catalyses a given reaction

Q69 : A fatty acid that is not synthesized in man is_____________?

A: Linoleic acid B: Oleic acid C: Palmitic acid D: Stearic acid

Q70 : In Niemann-Pick’s disease the following substrance accumulate in CNS in excess______________?

A: Glycerophosphatides B: Phosphoinositides C: Phosphosphingosides D: Glycerosphingosides

Q71 : HMG-CoA is formed during metabolism of all except______________?

A: Cholesterol B: Leucine C: Ketone bodies D: Bile acids

Q72 : Daily requirement of iron in man is_____________?

A: 1gm B: 10 microgram C: 10 mg D: 20 mg

Q73 : Non polar lipid act as______________?

A: Electrical insulators B: Irons C: Non electrical insulators D: Electrolytes

Q74 : Coenzyme responsible for single carbon transfer is______________?

A: Acetyl co enzyme A B: Biotin C: THF4 D: Pyridoxine

Q75 : Cholesterol levels in abnormal person should be preferably less than_____________?

A: 200 mg/dl B: 180 mg/dl C: 150 mg/dl D: 120 mg/dl

Q76 : In Hartnup’s disease _______ is excreted in the urine?

A: Ornithine B: Glutamine C: Tryptophan D: Phenylalanine

Q77 : The deficiency of thiamine can be identified by measuring the red cell______________?

A: Transketaolase B: Transaldolase C: Alpha ketoglutarate dehydrogenase D: Pyruvate dehydrogenase

Q78 : Somatomedin mediates________________?

A: Deposition of chondroitin sulfate B: Lipolysis C: Gluconeogenesis D: Decreased rate of glucose uptake by cells

Q79 : Elevated levels of serum glutamic oxaloacetic transaminase in indicative of______________?

A: Deficiency of glutamic acid B: Deficiency of oxaloacetic acid C: Liver disease D: All of the above

Q80 : Major source of ammonia in the kidney is___________?

A: Urea Aspartate B: Aspartate C: Glutamine D: Glutamate

Q81 : Acetyl Co-A acts as a substrate for all the enzymes except______________?

A: HMG-Co A synthase B: Malic enzyme C: Malonyl CoA synthetase D: Fatty acid synthetase

Q82 : Detoxification or protective synthesis occurs by____________?

A: Oxidation B: Reduction C: Conjugation D: Any of the above

Q83 : The patient suffered from hypogondism, failure to thrive, lose of taste and unable to maintain stability. This shows the deficiency of_____________?

A: Zinc B: Chromium C: Copper D: Potassium

Q84 : Which metabolite of TCA cycle is used in detoxification of ammonia in brain_____________?

A: Alpha ketoglutarate B: Ornithine C: Oxalocetate D: Oxalocetate

Q85 : The transmembrane adhesive molecules present in hemi desmosomes which specifically binds to basal lamina glycoprotein laminin are______________?

A: Integrin a6-B4 B: The catenins desmoplakin C: cadherins desmoglein D: a and B catenin

Q86 : Which of the following is correct of the pyruvate dehydrogenase enzyme complex ?

A: It is present in cytoplasm B: Catalyzes the conversion of pyruvate to oxaloacetate C: Requires TPP as cofactor D: Catalyzes a reversible reaction

Q87 : Cofactor required for lipoprotein lipase activity is_______________?

A: Apo A-II B: Apo C-II C: Apo C-III D: Apo B-II

Q88 : An essential for the conversion of glucose to glycogen in liver is____________?

A: UTP B: GTP C: Pyruvate Kinase D: Guanosine

Q89 : The combination of main supporting enzyme is called______________?

A: Apoenzyme B: Coenzyme C: Holoenzyme D: Constitutive enzyme

Q90 : The conversion of glucose 6-P to fructose 6-P is an example of which of the following reactions___________?

A: Phosphate transfer B: Isomerisation C: Dehydration D: Aldol cleavage

Q91 : Acetyl CoA is produced from which fuel sources_____________?

A: Carbohydrate B: Lipid C: Amino acids D: All of the above

Q92 : Enzymes concerned with the citric acid cycle are found in the____________?

A: Nucleus B: Ribosomes C: Mitochondria D: Nonparticulate cytoplasm

Q93 : The most abundant protein present in body is_____________?

A: Globulin B: Albumin C: Collagen D: Hemoglobin

Q94 : Multiienzyme complex in human_______________?

A: Fatty acid synthetase B: Malonyl CoA carboxylase C: Carbomoyl Phosphate synthetase D: Adenosine phospho ribosyl transferase

Q95 : An enzyme not involved in glycolysis is______________?

A: Enolase B: Phosphoglycero mutase C: Aldolase D: Glycerophosphate dehydrogenase

Q96 : Cane sugar is____________?

A: Glucose B: Surose C: Fructose D: Maltose

Q97 : Which of the following is most important content of diet ?

A: Protein B: Water C: Vitamin D: Minerals

Q98 : Which of the following about biological membrane is true ?

A: Lipid moiety is amphipathic B: Rigid assembly of protein, lipid and carbohydrate C: Symmertrical bi leaflet structures D: Lipid and protein moiety are held by covalent interaction

Q99 : Urinary protein is detected by______________?

A: Barfoed test B: Hay’s test C: Boiling test D: Ehrlich’s test

Q100 : A mutation that converts an amino acid codon to a stop codon is a_____________?

A: Nonsense mutation B: Transversion C: Silent mutation D: Frame shift mutation

Free Biochemistry MCQs Mock Test Online with Answers

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